Figure 8From: Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized miceIdentification of unique EE and TAM differentially expressed genes. Treatment specific differentially expressed genes were identified by excluding a list obtained using a more relaxed criteria (P1(t) > 0.9; |fold change| ≥ 1.4) for one treatment from the differentially expressed genes identified using the standard criteria (P1(t) > 0.999; |fold change| ≥ 1.5) of the second treatment to identify gene expression changes that were more likely to be unique to one treatment. (A) A liberal list of TAM-induced genes identified, using a relaxed criteria of P1(t) ≥ 0.9 and |fold change| ≥ ± 1.4, was excluded from the EE differentially expressed gene list using the standard selection criteria of P1(t) ≥ 0.999 and |fold change| ≥ ± 1.5 to identify 240 genes more likely to be differentially expressed by EE alone. (B) Using a similar approach, a list of 60 genes more likely to be differentially expressed by TAM alone was generated. Lists of EE and TAM specific genes are provided in Additional files 4 and 5.Back to article page