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Figure 5 | BMC Genomics

Figure 5

From: Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger

Figure 5

Model of the secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed. The A. niger gene designation is provided where previously known or, otherwise, the S. cerevisiae gene name is provided. Red, genes up-regulated by 3 conditions; orange, genes up-regulated by 2 conditions; yellow, genes up-regulated by 1 condition; light blue, genes down-regulated by 1 condition; blue, genes down-regulated by 2 conditions. N, nucleus; ER, endoplasmic reticulum; E, endosome; V, vacuole; G, Golgi. ERAD is ER-associated degradation.

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