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Table 1 Properties of artificial and real E. coli proteomes.

From: The relationships between the isoelectric point and: length of proteins, taxonomy and ecology of organisms

Analysed proteome Correlation coefficient for pI bias [%]
  acidic set basic set  
the average amino acid composition of E. coli proteins; the length of E. coli proteins 0.23 -0.28 -32 (-29 to -36)
equal frequencies of amino acids; the length of E. coli proteins 0.32 -0.28 -5 (-8 to -2)
the average amino acid composition of E. coli proteins; the uniform length distribution in the range of E. coli proteins 0.33 -0.48 -50 (-53 to -46)
the real proteome of E. coli K12 0.15 -0.25 -27
  1. Each of the first three proteomes was generated 100 times and the resulting correlation coefficients and the pI bias were averaged over 100 values. Correlation coefficients both for all generated artificial proteomes and the real proteome are statistically significant with p < 0.001.