Effect of engineered folding factors on the transcriptional level. A: Constitutively UPR induced 2F5 Fab producing SMD1168 (Fab+Hac1) compared to its control strain (containing only the Fab expression cassette). B: 2F5 Fab producing SMD1168 co-expressing S. cerevisiae PDI1 compared to the control strain. Both diagrams are ordered from the lowest to the highest log2 ratio. Colour legend as in figure 2.