Table 1 Interactome attack
From: Evidence for systems-level molecular mechanisms of tumorigenesis
Number of nodes remaining in the main component after selective removal of: | ||||||
|---|---|---|---|---|---|---|
N* | Hubs | CGPs | Same degree nodes | Difference** | ||
Prostate cancer | ||||||
Data set 1 | Down-regulated | 795 | 4,092 | 6,066 | 6,410 | 344 |
Up-regulated | 634 | 4,616 | 6,294 | 6,610 | 316 | |
Data set 2 | Down-regulated | 574 | 4,826 | 6,312 | 6,591 | 279 |
Up-regulated | 407 | 5,346 | 6,586 | 6,807 | 221 | |
Lung cancer | ||||||
Adenoid | Down-regulated | 476 | 5,112 | 6,460 | 6,719 | 259 |
Up-regulated | 187 | 6,134 | 6,830 | 6,966 | 136 | |
Carcinoid | Down-regulated | 786 | 4,119 | 5,965 | 6,368 | 403 |
Up-regulated | 518 | 5,002 | 6,421 | 6,736 | 315 | |
Squamous | Down-regulated | 458 | 5,171 | 6,479 | 6,716 | 237 |
Up-regulated | 525 | 4,974 | 6,380 | 6,640 | 260 | |
Colorectal cancer | ||||||
Down-regulated | 164 | 6,220 | 6,849 | 6,960 | 111 | |
Up-regulated | 289 | 5,726 | 6,709 | 6,858 | 149 | |