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Table 2 List of the identified eh1-like motifs in eight subclasses of invertebrate Fox proteins.

From: Prevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators

Subclass Protein Motifsa Homology to eh1 motifb Positionc Protein length Species Accession number
A        
  FoxA FAIKNII A 62.5% 243–250 321 H. vulgaris AAO92606
  FoxA FAIKNII A 62.5% 215–222 286 N. vectensis 42374841
  FoxA FSIDRIM H 50% 412–419 485 D. japonica 9309317
  FoxA FSITRLL P 75% 302–309 350 H. armigera 57791692
  FoxA FSITNLM S 62.5% 375–382 435 P. vulgata 22859616
  FoxA FSITRLL P 62.5% 300–307 349 B. mori 112983681
  FoxA FSITRLL P 62.5% 372–379 435 A. aegypti 108881332
  FoxA FSITRLL P 62.5% 374–381 437 A. gambiae 55233684
  FoxA FSINRLL P 62.5% 452–459 510 D. melangaster 7301684
  FoxA FSINRLL P 62.5% 370–377 431 T. castaneum 86515352
  FoxA FSITRLL P 75% 460–467 570 A. mellifera 110759792
  FoxA FSINSII P 62.5% 377–384 440 S. purpuratus 91983614
  FoxA5 FSISSLM N 62.5% 452–459 587 C. intestinalis AAB61227
  FoxA5 FSISNLM S 87.5% 342–349 403 B. floridae CAA65368
  FoxA5 FSISSLM N 62.5% 441–448 567 M. oculata AAB69278
B        
  FoxB FAIENLI G 62.5% 151–158 262 N. vectensis ABA03229
  FoxB FSIESIL S 75% 229–236 237 C. elegans AAA28104.1
  FoxB FTIESLI T 75% 222–229 372 D. melangaster 17977684
  FoxB FTIESLI T 75% 172–179 241 T. castaneum 91082601
  FoxB FTIESLI T 75% 189–196 198 A. gambiae EAA07672
  FoxB FTIENII A 75% 313–320 365 A. mellifera 110759134
  FoxB FTIENII S 87.5% 187–194 360 S. purpuratus NP999797
  FoxB FSIENII S 87.5% 305–312 475 C. intestinalis CAD58964
  FoxB FNIENII A 62.5% 181–188 289 B. floridae CAD44627
C        
  FoxC FTVDSLM N 50% 260–267 508 D. melangaster 17975538
  FoxC FTVDSLM N 50% 266–273 496 A. gambiae EAA11069
  FoxC FTVDSLM N 50% 251–258 412 A. aegypti 108876322
  FoxC FSVDALM N 50% 304–311 495 A. mellifera 110758357
  FoxC YTVDSLM A 50% 258–265 479 S. purpuratus 72007114
  FoxC FSVDNIM T 75% 233–300 497 B. floridae 57337372
D        
  FoxD FMISNLL K 75% 434–441 444 S. domuncula CAE51209
  FoxD FSMESIL S 62.5% 3–10 333 C. elegans 17536629
  FoxD FSISHII S 87.5% 393–400 455 D. japonica BAC10918
  FoxD FRIETLI G 50% 435–442 456 D. melangaster 17647421
  FoxD FSIENLI G 75% 491–498 504 A. aegypti 10886922
  FoxD FSIDALI G 62.5% 313–320 354 A. mellifera 110759337
  FoxD FTIDSLL N 62.5% 308–315 401 S. purpuratus 115953031
  FoxD FSIESLI G 62.5% 377–384 506 C. savignyi BAB68347
  FoxD FSIENII G 75% 311–318 402 B. floridae AF512537
E        
  FoxE FSIENII G 75% 207–214 393 C. intestinalis BAC57420
  FoxE4 FSIDNII A 75% 227–234 381 B. floridae 18653452
G        
  FoxG FSIENIL K 75% 12–19 318 M. leidyi AAN17798
  FoxG FSIRQML D 50% 16–23 260 D. japonica BAC10917
  FoxG FSILDLC P 37.5% 4–11 270 C. elegans 17569837
  FoxG FSINSIL P 50% 18–25 424 A. gambiae EAA43390
  FoxG FGMDRLL G 37.5% 284–291 424 A. gambiae EAA43390
  FoxG FSISSIL P 75% 156–163 444 T. castaneum 91080905
  FoxG FNMERLL A 37.5% 381–388 444 T. castaneum 91080905
  FoxG1 FSIRSIL P 62.5% 51–58 451 A. mellifera 110756018
  FoxG1 FSMERLL Q 37.5% 328–335 451 A. mellifera 110756018
  FoxG1 FSIDAIL A 62.5% 12–19 322 D. melangaster CAA46890
  FoxG2 FSIDAIL P 62.5% 62–69 445 D. melangaster CAA46891.1
  FoxG FSVESML S 62.5% 34–41 507 S. purpuratus 72179617
  FoxG FSVERLL S 75% 396–403 507 S. purpuratus 72179617
  FoxG1 FSIRRML S 62.5% 20–27 402 B. floridae AF067203
  FoxG1 FSVERLL S 75% 286–293 402 B. floridae AF067203
L        
  FoxL1 FTIDNII G 75% 356–363 365 D. melangaster Q02360
  FoxL1 FSIDNIL A 75% 299–306 521 S. purpuratus 72009133
Q        
  FoxQ1 FSIDSIL G 62.5% 251–258 408 S. purpuratus 82706210
  FoxQ1 FSIESIL S 75% 268–275 385 C. intestinalis 70569660
  FoxQ1 FSIDAIL S 75% 226–233 324 B. floridae CAH55831
  FoxQ2b FDVESLL R 50% 282–289 380 C. hemisphaerica 108796163
  FoxQ2a FSIENIL G 75% 325–332 387 C. hemisphaerica 108796161
  FoxQ2 FTIEAIL E 62.5% 221–228 230 C. elegans 17505695
  FoxQ2 FDVASLL A 50% 348–355 599 D. melangaster 66571262
  FoxQ2 FDVASLL A 50% 233–240 299 T. castaneum 91076112
  FoxQ2 FDVESLL R 50% 232–239 307 A. gambiae XP566358
  FoxQ2 FSIENLA Q 62.5% 4–11 329 S. purpuratus ABB89473
  FoxQ2 FSIDRLV G 62.5% 4–11 271 B. floridae AY163864
Orphans        
  Fox1 FRIEFLL K 50% 276–283 285 N. vectensis ABA03228
  Fox1 FSISKLI L 75% 211–218 218 S. domuncula CAE51213
  1. a The highly conserved core of the eh1-like motifs are indicated in bold.
  2. b The percent similarity between the identified Fox eh1-like motifs and the eh1 motif (FSISNILS) of the Drosophila engrailed homeodomain protein [7].
  3. c The location of the motifs within the amino acid sequence of the individual Fox proteins.