Table 5 Functional clustering of 147 fly orthologs of genes showing significant differences in expression between honey bee species, based on Gene Ontology-defined molecular functions

1

GO:0008233

peptidase activity

4

6

Rpn2, CG32130, CG4998, CG5798, east, CG4678

3.828e-05

2

GO:0005488

binding

2

15

CG3244, CG7966, CG3104, CG30387, Tsp96F, dsd, Hop, CG5001, CG6946, Rsf1, RpL6, Ef1γ, Rpb8, e, CG8745

0.007796

3

GO:0008092

cytoskeletal protein binding

4

6

Tctp, CLIP-190, coro, CG32030, chic, bif

1.823e-07

4

GO:0005215

transporter activity

2

6

CG32250, Tsp5D, PebIII, CG1358, CG6783, Cralbp

0.007066

5

GO:0008270

zinc ion binding

1

7

CG32486, Pax, Sodh-2, Nep2, S2P, Ance, Psa

1.021e-07

6

GO:0016462

pyrophosphatase activity

6

7

RhoBTB, Hsp83, Hsc70-4, Mnn1, Atet, CG33310, CG1271

1.276e-08

7

GO:0005488

binding

2

21

Tctp, CLIP-190, coro, CG32030, chic, bif, fru, CG3726, gro, CG32486, Pax, Sodh-2, Nep2, S2P, Ance, Psa, Cad87A, CG11105, BM-40-SPARC, Tsf1, CG4349

5.259e-05

8

GO:0003824

catalytic activity

2

33

Rpn2, CG32130, CG4998, CG5798, east, CG4678, wun, CG9265, Sulf1, pyd3, PGRP-SC2, Sirt2, α-Man-IIb, CG11257, CG9360, CG6439, antdh, CG10962, CG10638, b, CG6028, Mdh, ACXD, Gycβ100Bb100B, Pglym78, FKBP59, CG10903, CG10527, Pcmt, CG10178, Ugt86Dd, CG5037, Dat

5.480e-11

9

GO:0016740

transferase activity

3

7

CG10903, CG10527, Pcmt, CG10178, Ugt86Dd, CG5037, Dat

4.211e-06

10

GO:0016787

hydrolase activity

3

13

Rpn2, CG32130, CG4998, CG5798, east, CG4678, wun, CG9265, Sulf1, pyd3, PGRP-SC2, Sirt2, α-Man-IIb

1.016e-07

11

GO:0003676

nucleic acid binding

3

5

CG6946, Rsf1, RpL6, Ef1γ, Rpb8

0.000773

12

GO:0043167

ion binding

3

12

CG32486, Pax, Sodh-2, Nep2, S2P, Ance, Psa, Cad87A, CG11105, BM-40-SPARC, Tsf1, CG4349

1.837e-12

13

GO:0005515

protein binding

3

9

Tctp, CLIP-190, coro, CG32030, chic, bif, fru, CG3726, gro

0.000444

14

GO:0016491

oxidoreductase activity

3

6

CG11257, CG9360, CG6439, antdh, CG10962, CG10638

3.828e-05