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Table 3 GSEA of DEX-treated primary chondrocytes.

From: Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development

Gene set name Size ES NES NOM p-val FDR q-val
Metabolism 196 0.471 1.935 <0.001 0.016
Extracellualr Matrix 228 0.451 1.878 <0.001 0.016
Fkbp 33 0.559 1.696 0.011 0.054
Integrin_Related 173 0.407 1.643 <0.001 0.001
Angiogenesis 57 0.479 1.610 0.012 0.065
Kinase_1 499 0.343 1.549 <0.001 0.092
Tumor Suppressor 48 0.457 1.492 0.037 0.126
Catalytic 245 0.337 1.420 0.008 0.172
Hepatocyte 19 0.529 1.406 0.104 0.161
D3 Vs D15_2 497 0.304 1.368 0.004 0.194
Igf 48 0.412 1.348 0.093 0.208
Cyclin 224 0.322 1.344 0.028 0.199
Actin_Cytoskel 38 0.426 1.325 0.124 0.213
Structure 151 0.332 1.312 0.053 0.219
Cytoplasm 411 0.292 1.300 0.023 0.224
Adipose 70 0.368 1.285 0.116 0.232
Gtpase Activity 73 0.363 1.280 0.113 0.230
Cartilage 28 0.432 1.262 0.169 0.246
Chemokine 31 -0.779 -2.40 <0.001 0
Cytokine 127 -0.579 -2.31 <0.001 0
Growth Factor 106 -0.517 -2.01 <0.001 7.698E-04
Interleukinrelated 175 -0.469 -1.98 <0.001 9.475E-04
Bone 16 -0.577 -1.51 0.051 8.945E-02
Creb_Atf3 30 -0.469 -1.43 0.065 1.300E-01
Dusp 20 -0.508 -1.40 0.102 1.418E-01
Blood 111 -0.351 -1.37 0.037 1.425E-01
3vs15_1.5x_3 496 -0.288 -1.35 0.002 1.518E-01
Protease_2 268 -0.306 -1.35 0.015 1.411E-01
Nuc_Hormone_Receptor 55 -0.381 -1.32 0.086 1.570E-01
Tf_Repress 55 -0.380 -1.32 0.091 1.498E-01
3vs15_1.5x_4 497 -0.272 -1.28 0.011 1.817E-01
Erk_Related 40 -0.385 -1.25 0.157 2.169E-01
  1. ES, enrichment score
  2. NES, normalized enrichment score
  3. FDR q-val, false discovery rate and multiple testing corrections (q-value)
  4. NOM p-val; the uncorrected p-value