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Figure 2 | BMC Genomics

Figure 2

From: EDGEdb: a transcription factor-DNA Interaction database for the analysis of C. elegans differential gene expression

Figure 2

EDGEdb gene, DNA bait and expression pages. (A) EDGEdb daf-3 gene page. The top section contains the different daf-3 gene identifiers, each of which is linked to WormBase. In addition, it contains a link to Worfdb, and the detailed TF page (red circle). The middle section contains the genome view of the daf-3 gene. The third section lists the DNA baits associated with daf-3 (i.e. the daf-3 promoter, Pdaf-3) and their corresponding yeast one-hybrid interactors (i.e. TFs that bind to Pdaf-3). The bottom section includes the DNA baits bound by the TF DAF-3 (blue circle). By clicking this one goes to the Pmdl-1 DNA bait page. (B) EDGEdb DNA bait page for Pmdl-1. This page displays the DNA bait sequence and genomic coordinates; IDs of the gene corresponding to the DNA bait and link to the gene page (red circle). The middle section contains the genome browser. In the bottom section, the list of the interactors found with the DNA bait and links to the relevant experiments and gene pages are shown (blue circle). By clicking this link one goes back to the daf-3 gene page. A link to the page containing the expression patterns driven by the DNA bait is included (green circle). By clicking this one goes to the expression page for Pmdl-1. (C) Expression data page for Pmdl-1. From top to bottom: GFP expression driven by Pmdl-1 in wild type animals, in daf-3(RNAi) animals, in control RNAi animals, and in dauer animals. See Deplancke et al. [5] for details.

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