Figure 3

Prediction accuracy. Box plots of the accuracy (sensitivity or specificity) of the prediction of the differentiation state of embryonic stem cells using "n" (2 to 20) mRNA transcript levels as diagnostic signature patterns. The box has lines at the lower quartile (25^th), median (50^th), and upper (75^th) quartile values. The whiskers are lines extending 1.5 × (inter-quartile ranges) from each end of the box with outliers ('+') marked. The box plot shows the average prediction accuracy (based on 500 random divisions of the sample set into training and test sub-sets) for the 30,000 diagnostic models created for each "n". The diagnostic models were built using G_stemness (size = 114), G_secreted proteins (size = 21), G_membrane proteins (size = 25) and G_{extracellular} proteins (size = 46) separately. Extracellular proteins include secreted and membrane proteins.