Figure 2

Comparison of CGH and transcriptome data. Plot of log₂ [gDNA _Sliv /gDNA _Scoe ] (x-axis) vs max(log₂ [mRNA _Scoe /gDNA _Scoe ]) (y-axis). The y-axis values correspond to the maximum gene expression levels observed considering all analyzed samples (includes both R5^- and SMM). Genes belonging to GI-1 (), GI-2 (×), GI-3 (○), GI-4 (□), GI-5 (◇) and all other smaller islets (black +) are shown alongside genes conserved in both S. coelicolor and S. lividans (green +). Genes in the region left of and above the dotted lines are those that are highly expressed in S. coelicolor but absent in S. lividans. High expression in this case was defined as max(log₂ [mRNA _Scoe /gDNA _Scoe ]) ≥ 2.0 which corresponds to the top 14 percentile of gene expression values. The plot shows that a large fraction of genes absent in S. lividans have low expression levels in S. coelicolor. Nevertheless, there are some prominent examples of highly expressed genes within certain S. coelicolor genomic islands. This includes several genes from GI-2.