Figure 1

Examples of tissue-specific molecular markers in the E14.5 mouse embryo. A and B. Prostaglandin D2 synthase (brain) (Ptgds) (Genepaint set ID HD33, image 2C) expression is exclusive to the meninges (me), choroid plexi (cp, A) and gonads (g, B). C. Lysyl oxidase-like 3 (Lox13) (MH1813, 4A) is exclusively expressed in cartilage (ca). D and E. Ribonuclease T2 (Rnaset2) (MH1633, 1A, 5A) is a suitable marker for lens (le, D) and choroid plexi (cp, E). F and G. Acetyl-Coenzyme A synthetase 2 (AMP forming)-like (Acas2l) (MH1439, 4C, 4B) marks the ventricular zones of the nervous system (vz, F), including that of the spinal cord (sp, G), and liver (not shown). H. The gene Carboxypeptidase N polypeptide 1 (Cpn1) (MH1654, 5B) marks liver (li), pancreas (pa) and stomach (so). I and J. Expression of Alcohol dehydrogenase 1 (class I) (Adh1) (MH1744, 3D) is seen in adrenal gland (a, I), lung mesenchyme (lu, I) and nasal epithelium (n, J). K and L. Phospholipase A2 (Pla2g2f) (MH1625, 3A) expression is restricted to the lung (lu, K) and the adrenal gland (a, L). M and N. Glucokinase (Gck) (MH1608, 4C) is exclusive to the ventromedial nucleus of the hypothalamus (vt), preoptic area, anterior pituitary (pi, M) and pancreas (pa, N), O – Q. Expression of Carbonic anhydrase 14 (Car14) (MH1292, 3C, 1A) in choroids plexi (cp, O and P) and retina (re, Q).