Table 2 Maximum power as a function of the number of genotyping(G = J × K), number of replicates giving maximum power (K o (G)), number of replicates (K) at 95% of the maximum power at specific experimental and genetic parameters and the power at K = 1 when assuming no machine replicability variability (m = 1)
Situation | N | MOI | R 2 | α | m | MAF | p r | G = 40 | G = 80 | G = 160 | G = 320 | G = 640 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 10000 | R | 2.2 | 0.0001 | 2.25 | 0.20 | 0.9 | 38%, 2, (2), 82% | 54%, 4, (3–4), 85% | 64%,6, (4–7), 87% | 72%, 10, (5–16), 87% | 77%, 13, (6–27), 88% |
2 | 10000 | R | 2.0 | 0.001 | 2.25 | 0.20 | 0.9 | 43%, 2, (2), 79% | 56%, 4, (3–4), 81% | 65%, 7, (4–7), 82% | 71%, 11, (6–16), 83% | 75%, 16, (7–32), 83% |
3 | 10000 | R | 1.8 | 0.01 | 2.25 | 0.20 | 0.9 | 50%, 2, (2), 79% | 62%, 4, (3–4), 80% | 68%, 7, (5–7), 80% | 72%, 13, (6–16), 80% | 75%, 20, (7–32), 81% |
4 | 10000 | R | 2.2 | 0.0001 | 2.25 | 0.15 | 1 | 69%, 2, (2), 98% | 84%, 4, (3–4), 99% | 90%, 6, (3–7), 99% | 95%, 10, (4–16), 99% | 96%, 13, (4–32), 99% |
5 | 10000 | R | 2.2 | 0.0001 | 2.0 | 0.15 | 1 | 75%, 2, (2), 98% | 87%, 4, (2–4), 99% | 92%, 5, (3–7), 99% | 95%, 8, (3–16), 99% | 97%, 12 (3–32), 99% |
6 | 10000 | R | 2.0 | 0.0001 | 2.25 | 0.15 | 1 | 43%,2, (2), 86% | 59%, 4, (3–4), 89% | 70%, 6, (4–7), 90% | 77%, 10, (5–16), 91% | 82%, 13, (6–28), 91% |
7 | 10000 | R | 2.0 | 0.0001 | 2.0 | 0.15 | 1 | 49%, 2 (2), 86% | 63%, 4, (3–4), 89% | 73%, 5, (4–7), 90% | 79%, 8, (4–16), 91% | 83%, 12, (5–27), 91% |
8 | 2000 | D | 1.5 | 0.0001 | 2.25 | 0.15 | 0.9 | 57%, 3, (2–3), 94% | 73%, 4, (3–6), 96% | 82%, 6, (4–10), 96% | 88%, 10, (4–18), -- | 91%, 13, (5–32), -- |
9 | 2000 | D | 1.5 | 0.0001 | 2.25 | 0.15 | 1 | 65%, 3, (2–3), 97% | 80%, 4, (3–6),98% | 88%, 6, (3–9), 98 | 92%, 10, (4–21), -- | 95%, 13, (4–40), -- |
10 | 2000 | D | 1.5 | 0.0001 | 2.0 | 0.15 | 1 | 70%, 2, (2–3), 97% | 83%, 4, (3–6), 98% | 90%, 5. (3–10), 98% | 94%, 8, (3–20), -- | 96%, 12, (4–37), -- |