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Table 3

From: Mouse SNP Miner: an annotated database of mouse functional single nucleotide polymorphisms

PolyPhen

Deleterious

Not-deleterious

Not predicted

PANTHER

   

Deleterious

1,647

2,092

73

not-deleterious

1,857

11,569

310

Not predicted

1,818

5,888

1,889

  1. PolyPhen and PANTHER predictions overlap significantly, with 6.1% of missense mutations categorized as detrimental by both algorithms.
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BMC Genomics

ISSN: 1471-2164

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