Figure 5From: Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoidsLPS-induced changes in miRNA-223 expression in the mouse lung. Lungs were removed from saline-challenged (A-D) and LPS-challenged (E-H) mice at 3 hrs post-challenge and tissue slices were examined by in situ hybridisation using either a miRNA-223-specific (A, B, E, F) or scrambled (C, G) LNA probe, or histologically following cresyl violet staining (D, H). Bronchial (BE) and alveolar (AE) epithelia, as well as the vascular endothelium (VE) and leukocytes (L) are indicated.Back to article page