TF Circle. The TF circle depicts all the TFs and TF pairs, which are significantly related to at least one module. Related modules are represented by strings in the vicinity of the relevant TF or, in the case of a TF pair, in the vicinity of the line connecting both TFs. The strings are made up out of three parts. The first number represents the number that was assigned to the module. The second number indicates the number of genes in the module. The third part is the discretized expression pattern of the genes in the module. Here, an 'x' indicates the irrelevance (don't care) of a particular cultivation parameter. The color coding of the circle is based on the discretized expression representation of the modules. The placement of the TFs (near the center or the edge) is for reasons of visibility only.