Figure 2
From: The functional modulation of epigenetic regulators by alternative splicing
Impact of alternative splicing in catalytic domains. In all cases the part of the protein affected by alternative splicing is shown in yellow, while the remaining of the protein is shown in blue. (A) Domain DEXHC of human chromatin remodelling SMARCA1. Alternative splicing results in the loss of a α-helix. (B) Domain PI3_PI4_KINASE of kinase PRKDC. Alternative splicing results in the loss of a sequence stretch that has very distant ends. The figures were obtained using the MOLSCRIPT software [65].