Table 2 Cases for which alternative splicing sequence changes mainly affect catalytic domains
From: The functional modulation of epigenetic regulators by alternative splicing
Gene name | Species | Reference Isoform Size | Alternative Isoform Size | Domains affected |
|---|---|---|---|---|
SUV39H2 | H.s. | 410 | 230 | PRESET, SET |
SMARCA1 (SNF2L) | H.s. | 1054 | 1033 | DEXHC |
PRKDC (DNA-PK) | H.s. | 4127 | 4097 | PI3_PI4 KINASE |
RPS6KA5 (MSK1) | H.s. | 802 | 549 | PKINASE |
EZH2 | H.s. | 751 | 376 | SET |
EHMT2 (G9a) | H.s. | 1210 | 202 | ANK, PRESET, SET* |
CARM1 (PRMT4) | H.s. | 608 | 412 | SKB1 |
SETDB1 | H.s. | 1290 | 397 | MBD, PRESET, SET, TUDOR |
EHMT1 | H.s. | 1267 | 1153 | SET |
FBXL11 (JHDM1A) | H.s. | 1162 | 856 | JMJC |
AOF2 (LSD1) | H.s. | 876 | 852 | AMINO_OXIDASE |
GSG2 (HASPIN) | H.s. | 798 | 314 | PKINASE |
PRDM2 (RIZ1) | H.s. | 1718 | 1481 | SET |
Setdb1 | M.m. | 1308 | 488 | MBD, PRESET, SET |
Htatip | M.m | 546 | 492 | MOZ_SAS |
Fbxl10 (Jhdm1b) | M.m. | 1309 | 776 | JMJC |
Fbxl10 (Jhdm1b) | M.m | 1309 | 656 | JMJC |
Jmjd1b (Jhdm2b) | M.m | 1562 | 1124 | JMJC |
fbxl10 (Jhdm1b) | X.l. | 1259 | 738 | JMJC |
mez2 | Z.m. | 894 | 624 | SET |