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Table 3 Comparison of expression ratios in motor cortex and spinal cord

From: Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis

  

Expression Ratios

 

Gene Symbol

UniGene ID

Motor Cortex

Spinal Cord

Comparison

AQP1

Hs.76152

2.52

2.84

==

MT2A

Hs.418241

2.43

4.66

=

SLC14A1

Hs.101307

2.15

1.91

==

ANXA2

Hs.511605

2.06

4.49

=

MT1X

Hs.374950

2.02

1.99

==

FCGBP

Hs.111732

2.00

3.14

=

DSCR1L1

Hs.440168

0.49

0.49

==

PCP4

Hs.80296

0.49

0.60

==

SCG5

Hs.156540

0.48

0.58

==

UCHL1

Hs.518731

0.48

0.48

==

GABRA1

Hs.175934

0.47

0.56

==

EGR1

Hs.326035

0.46

0.42

==

OLFM1

Hs.522484

0.43

0.50

==

VSNL1

Hs.444212

0.35

0.38

==

SNAP25

Hs.167317

0.31

0.82

<>

MDH1

Hs.526521

0.41

0.68

<>

CHN1

Hs.380138

0.42

0.71

<>

EIF4A2

Hs.478553

0.45

0.98

<>

RTN1

Hs.368626

0.46

0.71

<>

ATP5A1

Hs.298280

0.48

1.13

<>

NDUFA4

Hs.50098

0.48

0.73

<>

PCSK1

Hs.78977

0.39

1.73

<>

CHGB

Hs.516874

0.39

1.65

<>

  1. Expression ratios for candidate genes identified in the present report (Motor Cortex) are compared to those found by Dangond et al. [4] (Spinal Cord), giving a correlation coefficient of r = 0.85. Spinal cord data were retrieved from the Gene Expression Omnibus Database (GEO, series GSE833) and processed as described in the Methods section.
  2. == both tissues give the same result, differing ≤1.5-fold
  3. = both tissues give the same result, differing >1.5-fold
  4. <> both tissues give different results (up- vs. down-regulation or deregulation vs. constancy, defining constancy as a ≤1.5-fold deregulation)