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Table 3 Comparison of expression ratios in motor cortex and spinal cord

From: Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis

   Expression Ratios  
Gene Symbol UniGene ID Motor Cortex Spinal Cord Comparison
AQP1 Hs.76152 2.52 2.84 ==
MT2A Hs.418241 2.43 4.66 =
SLC14A1 Hs.101307 2.15 1.91 ==
ANXA2 Hs.511605 2.06 4.49 =
MT1X Hs.374950 2.02 1.99 ==
FCGBP Hs.111732 2.00 3.14 =
DSCR1L1 Hs.440168 0.49 0.49 ==
PCP4 Hs.80296 0.49 0.60 ==
SCG5 Hs.156540 0.48 0.58 ==
UCHL1 Hs.518731 0.48 0.48 ==
GABRA1 Hs.175934 0.47 0.56 ==
EGR1 Hs.326035 0.46 0.42 ==
OLFM1 Hs.522484 0.43 0.50 ==
VSNL1 Hs.444212 0.35 0.38 ==
SNAP25 Hs.167317 0.31 0.82 <>
MDH1 Hs.526521 0.41 0.68 <>
CHN1 Hs.380138 0.42 0.71 <>
EIF4A2 Hs.478553 0.45 0.98 <>
RTN1 Hs.368626 0.46 0.71 <>
ATP5A1 Hs.298280 0.48 1.13 <>
NDUFA4 Hs.50098 0.48 0.73 <>
PCSK1 Hs.78977 0.39 1.73 <>
CHGB Hs.516874 0.39 1.65 <>
  1. Expression ratios for candidate genes identified in the present report (Motor Cortex) are compared to those found by Dangond et al. [4] (Spinal Cord), giving a correlation coefficient of r = 0.85. Spinal cord data were retrieved from the Gene Expression Omnibus Database (GEO, series GSE833) and processed as described in the Methods section.
  2. == both tissues give the same result, differing ≤1.5-fold
  3. = both tissues give the same result, differing >1.5-fold
  4. <> both tissues give different results (up- vs. down-regulation or deregulation vs. constancy, defining constancy as a ≤1.5-fold deregulation)