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Table 4 Summary of the identified promoter motifs in the 23 human RefSeq genes of group b

From: Inference of transcriptional regulation using gene expression data from the bovine and human genomes

Motif (Seqs; Sites)

Best hit

Score (S)

p-value (P)

CorrectedP

b1 h (17; 45)

SP1_Q2_01 (10)

0.87

5.71 × 10-1

0.62

 

SP1_Q4_01 (13)

0.98

7.82 × 10-1

0.78

b3 h (7; 10)

AMEF2_Q6 (18)

0.87

4.00 × 10-3

0.06

b5 h (15; 29)

E47_01 (15)

0.99

1.10 × 10-2

0.06

b8 h (4; 6)

AP2_Q3 (16)

0.78

9.00 × 10-3

0.06

b11 h (6; 6)

MZF 5–13* (10)

0.67

5.00 × 10-3

0.08

  1. Promoter sequences for the 23 human genes were examined with MEME for prediction of motifs common to the group. The resulting motifs were then compared to entries in the TRANSFAC and JASPAR databases for identification. For each identified motif the dissimilarity score (S) and the p-value (P) are shown. Corrected p-value for each match is based on an estimated FDR of 10%. Matches to the JASPAR database are marked by (*). Sequence logos for the matrices are given in Figure 3.
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BMC Genomics

ISSN: 1471-2164

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