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Table 4 Differential expressed detoxification genes in the small intestine after 24 h fasting.

From: Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting

Gene symbol Affy probe set ID A value SD WT 0 hr SD WT 24 hr Fold change P-value Gene name
CYPP450s
Cyp4a10 1424853_s_at 7.4 0.96 0.37 3.6 0.0019 Cytochrome P450, family 4, subfamily a, polypeptide 10
Cyp27a1 1417590_at 8.4 0.12 0.50 3.1 0.0001 Cytochrome P450, family 27, subfamily a, polypeptide 1
Cyp2j6 1417952_at 8.3 0.22 0.11 2.3 0.0000 Cytochrome P450, family 2, subfamily j, polypeptide 6
Cyp4b1 1416194_at 9.7 0.20 0.22 2.2 0.0000 Cytochrome P450, family 2, subfamily c, polypeptide 29
Cyp3a11 1416809_at 11.0 0.07 0.10 1.3 0.0057 Cytochrome P450, family 3, subfamily a, polypeptide 11
GSTs
Mgst1 1415897_a_at 11.1 0.05 0.08 1.3 0.0014 Microsomal glutathione S-transferase 1
Gstp1 1449575_a_at 11.9 0.14 0.13 -1.4 0.0027 Glutathione S-transferase, pi 1
Gstm5 1416842_at 7.1 0.12 0.05 -1.5 0.0002 Glutathione S-transferase, mu 5
Gstt1 1418186_at 7.1 0.21 0.06 -1.7 0.0001 Glutathione S-transferase, theta 1
Gstm3 1427473_at 5.4 0.44 0.45 -2.6 0.0006 Glutathione S-transferase, mu 3
Gstm4 1424835_at 4.5 0.60 0.38 -2.7 0.0009 Glutathione S-transferase, mu 4
Gstm3 1427474_s_at 9.2 0.36 0.79 -2.8 0.0027 Glutathione S-transferase, mu 3
SULTs
Sult1d1 1418138_at 9.9 0.15 0.33 1.7 0.0017 Sulfotransferase family 1D, member 1
Chst4 1453393_a_at 4.7 0.04 0.08 1.4 0.0008 Carbohydrate (chondroitin 6/keratan) sulfotransferase 4
AKRs
Akr1b7 1423556_at 10.3 0.04 0.63 2.5 0.0008 Aldo-keto reductase family 1, member B7
  1. A = the average log2 transformed expression value of normal fed and 24 hours fasted mice (n = 3), SD = standard deviation (n = 3), WT = wild-type mice.
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BMC Genomics

ISSN: 1471-2164

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