Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting

BMC Genomics

Table 4 Differential expressed detoxification genes in the small intestine after 24 h fasting.

Gene symbol	Affy probe set ID	A value	SD WT 0 hr	SD WT 24 hr	Fold change	P-value	Gene name
CYPP450s
Cyp4a10	1424853_s_at	7.4	0.96	0.37	3.6	0.0019	Cytochrome P450, family 4, subfamily a, polypeptide 10
Cyp27a1	1417590_at	8.4	0.12	0.50	3.1	0.0001	Cytochrome P450, family 27, subfamily a, polypeptide 1
Cyp2j6	1417952_at	8.3	0.22	0.11	2.3	0.0000	Cytochrome P450, family 2, subfamily j, polypeptide 6
Cyp4b1	1416194_at	9.7	0.20	0.22	2.2	0.0000	Cytochrome P450, family 2, subfamily c, polypeptide 29
Cyp3a11	1416809_at	11.0	0.07	0.10	1.3	0.0057	Cytochrome P450, family 3, subfamily a, polypeptide 11
GSTs
Mgst1	1415897_a_at	11.1	0.05	0.08	1.3	0.0014	Microsomal glutathione S-transferase 1
Gstp1	1449575_a_at	11.9	0.14	0.13	-1.4	0.0027	Glutathione S-transferase, pi 1
Gstm5	1416842_at	7.1	0.12	0.05	-1.5	0.0002	Glutathione S-transferase, mu 5
Gstt1	1418186_at	7.1	0.21	0.06	-1.7	0.0001	Glutathione S-transferase, theta 1
Gstm3	1427473_at	5.4	0.44	0.45	-2.6	0.0006	Glutathione S-transferase, mu 3
Gstm4	1424835_at	4.5	0.60	0.38	-2.7	0.0009	Glutathione S-transferase, mu 4
Gstm3	1427474_s_at	9.2	0.36	0.79	-2.8	0.0027	Glutathione S-transferase, mu 3
SULTs
Sult1d1	1418138_at	9.9	0.15	0.33	1.7	0.0017	Sulfotransferase family 1D, member 1
Chst4	1453393_a_at	4.7	0.04	0.08	1.4	0.0008	Carbohydrate (chondroitin 6/keratan) sulfotransferase 4
AKRs
Akr1b7	1423556_at	10.3	0.04	0.63	2.5	0.0008	Aldo-keto reductase family 1, member B7

A = the average log2 transformed expression value of normal fed and 24 hours fasted mice (n = 3), SD = standard deviation (n = 3), WT = wild-type mice.

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