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Table 4 Enriched GO categories for upregulated genes, sorted by p-value

From: Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

GO categories Observed Expected Ratio p-value
Biological process     
phosphate transport 8 0.98 8.16 5.27E-06
cell adhesion 22 8.15 2.7 1.81E-05
anion transport 9 2.15 4.19 0.000297
inorganic anion transport 8 1.77 4.52 0.000378
axonogenesis 5 0.66 7.58 0.000471
neuron morphogen. during different. 5 0.74 6.76 0.000807
neurite morphogenesis 5 0.74 6.76 0.000807
neuron development 5 0.98 5.1 0.002889
cell development 6 1.45 4.14 0.003197
neuron differentiation 5 1.14 4.39 0.005565
neurogenesis 5 1.19 4.2 0.006627
Molecular Function     
extracellular matrix struct. const. 10 1.25 8 4.11E-07
integrin binding 4 0.43 9.3 0.000833
copper ion binding 5 0.82 6.1 0.00128
Cellular Component     
extracellular matrix 22 3.55 6.2 5E-12
collagen 8 0.5 16 2.08E-08
extracellular region 35 14.17 2.47 2.83E-07
fibrillar collagen 4 0.16 25 1.24E-05
actin cytoskeleton 8 2.78 2.88 0.006602