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Table 4 Enriched GO categories for upregulated genes, sorted by p-value

From: Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

GO categories

Observed

Expected

Ratio

p-value

Biological process

    

phosphate transport

8

0.98

8.16

5.27E-06

cell adhesion

22

8.15

2.7

1.81E-05

anion transport

9

2.15

4.19

0.000297

inorganic anion transport

8

1.77

4.52

0.000378

axonogenesis

5

0.66

7.58

0.000471

neuron morphogen. during different.

5

0.74

6.76

0.000807

neurite morphogenesis

5

0.74

6.76

0.000807

neuron development

5

0.98

5.1

0.002889

cell development

6

1.45

4.14

0.003197

neuron differentiation

5

1.14

4.39

0.005565

neurogenesis

5

1.19

4.2

0.006627

Molecular Function

    

extracellular matrix struct. const.

10

1.25

8

4.11E-07

integrin binding

4

0.43

9.3

0.000833

copper ion binding

5

0.82

6.1

0.00128

Cellular Component

    

extracellular matrix

22

3.55

6.2

5E-12

collagen

8

0.5

16

2.08E-08

extracellular region

35

14.17

2.47

2.83E-07

fibrillar collagen

4

0.16

25

1.24E-05

actin cytoskeleton

8

2.78

2.88

0.006602