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Table 1 NF-κB binding sites in NOS-2 promoters. Sequences were scanned with Match using TRANSFAC Professional 8.2 and minimizing false positives. Coincidence with experimentally demonstrated κB sites is indicated

From: Identification of conserved domains in the promoter regions of nitric oxide synthase 2: implications for the species-specific transcription and evolutionary differences

 

Position

Strand

Matrix match

Comments

Human

-119

+

0.908

Controversial (8)

 

-4357

-

0.987

c-Rel.

 

-5213

-

0.935

Described (13)

 

-5802

-

0.908

Described (13)

 

-8279

+

0.913

Described (19)

Mouse

+192

+

0.894

 
 

+191

+

0.913

 
 

-103

-

0.917

Described (11, 31)

 

-996

+

0.989

c-Rel.

 

-997

-

0.999

 
 

-998

+

0.979

Described (11, 31)

 

-2796

+

0.918

 
 

-5347

+

0.971

 
 

-5343

-

0.967

 
 

-5342

+ & -

0.997

 

Rat

-1601

-

0.917

 
 

-2394

-

0.989

c-Rel.

 

-2399

+

0.993

 
 

-2458

+

0.989

c-Rel.

 

-2459

-

0.999

 
 

-2460

+

0.979

 
 

-8999

+

0.980

c-Rel.

 

-9000

-

0.937

 
 

-9655

-

0.936