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Table 6 Predicted functions of down-regulated genes

From: A rapid genome-wide response to Drosophila melanogaster social interactions

Gene identifier Gene name Location GO molecular function GO biological process Immune response
CG6639   36C9 chymotrypsin activity proteolysis y
CG4740 AttC 50A3 unknown antibacterial humoral response y
CG18372 AttB 51C1 unknown antibacterial humoral response y
CG10146 AttA 51C1 unknown antibacterial humoral response y
CG4757   86D5 carboxylesterase unknown y
CG15066 IM23 55C4 unknown antibacterial humoral response y
CG8175 Mtk 52A1 unknown antibacterial/antifungal humoral response y
CG1367 CecA2 99E2 unknown antibacterial humoral response y
CG13422   57A4 glucosidase antibacterial defense response y
CG10810 Drs 63D2 ion channel inhibitor antibacterial/antifungal humoral response y
CG10816 Dro 51C1 unknown antibacterial humoral response y
CG18563   36C9 trypsin activity proteolysis y
CG1365 CecA1 99E2 unknown antibacterial humoral response y
CG6687   88E3 serine-type endopeptidase inhibitor; ATP synthase ATP synthesis coupled protein transport; proteolysis y
CG18108 IM1 55C4 unknown defense response y
CG9989   98E1 unknown unknown n
CG5550   53D10 receptor binding defense response y
CG2217   99F3-4 unknown unknown n
CG15065   55C4 unknown unknown y
CG14745 PGRP-SC2 44E2 peptidoglycan binding defense response y
CG9434 Fst 85E2 unknown response to cold y
CG2042   39D1 unknown unknown n
CG16772   38A8 unknown unknown n
CG13947   21E2 unknown unknown n
CG18279 IM10 50A5 unknown antibacterial humoral response y
CG13482   70D5 unknown unknown y
CG18106 IM2 55C4 unknown defense response y
CG11992 Rel 85C3 transcription factor defense response y
CG16844 IM3 55C4 unknown antibacterial humoral response y
CG15231 IM4 57B3 unknown defense response y
CG18067   57A5 unknown unknown y
CG10332/IM18   59F4 unknown defense response y
CG10947   38C6 unknown unknown n
  1. Twenty-seven of the 33 down-regulated genes likely function in the immune response. CG15065 is closely related to IM2. Immune responsive genes are overrepresented in this data set (p = 3.163 × 10-32, Fisher's Exact Test).