Table 3 Functional modules for gastric cancer (FDR ≤ 0.1)
From: GO-2D: identifying 2-dimensional cellular-localized functional modules in Gene Ontology
Dimension | Biological Process Name (# of genes d in BP) | Cellular Component Name (# of genes d in CC) | # of genes d in 2D module | Observed P Value |
|---|---|---|---|---|
1Db | rRNA processing (46) | Â | Â | 1.07E-05 |
| Â | regulation of cyclin dependent protein kinase activity (28) | --- | --- | 2.26E-05 |
| Â | Digestion (26) | Â | Â | 6.04E-04 |
| Â | traversing start control point of mitotic cell cycle (5) | Â | Â | 1.18E-03 |
2Dc | rRNA processing (46) | protein complex (1135) | 22 | 2.22E-04 |
| Â | rRNA processing (46) | nucleolus (73) | 20 | 1.34E-03 |
| Â | regulation of cyclin dependent protein kinase activity (28) | nucleus (2425) | 18 | 5.27E-05 |
| Â | Digestion (26) | cell (6889) | 16 | 4.09E-04 |
| Â | traversing start control point of mitotic cell cycle (5) | nucleus (2425) | 5 | 1.18E-03 |
| Â | electron transport (229) | endoplasmic reticulum (378) | 49 | 1.53E-04 |
| Â | electron transport (229) | membrane (2978) | 102 | 2.66E-04 |
| Â | electron transport (229) | microsome (76) | 29 | 7.80E-04 |
| Â | cell cycle arrest (50) | cytoplasm (2362) | 14 | 4.77E-04 |
| Â | negative regulation of cell proliferation (107) | cytoplasm (2362) | 37 | 8.41E-04 |
| Â | NLS-bearing substrate import into nucleus (12) | nuclear part (465) | 5 | 1.18E-03 |
| Â | one-carbon compound metabolism (24) | intracellular membrane-bound organelle (3675) | 7 | 1.67E-03 |