Phlebotomus papatasi midgut carboxypeptidase like proteins. (A) Phylogenetic analysis of carboxypeptidases from Caenorhabditis elegans (Ce), Aedes aegypti (Ae), Anopheles gambiae (Ag), Drosophila melanogaster (Dm), Ochlerotatus triseriatus (Ot), Tribolium castaneum (Tc), and Phlebotomus papatasi (Pp). Accession numbers are indicated in parenthesis and node support indicated by the bootstrap values. (B) Sequence comparison of midgut Phlebotomus papatasi carboxypeptidase A (PpCpepA) and carboxypeptidase B (PpCpepB). The predicted signal peptide is underlined and the residues necessary for zinc binding (H and E) are indicated by (*).