Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c- Myc in a model of plasma cell neoplasia

Table 1 Summary of mouse tumors studied by Affymetrix microarray profiling

Tumors	Cited as	Exogenous gene effect	Tumor type	Site of origin	N
PCT-1	ABLMYCPC	v-Abl + c-Myc	Virus-accelerated ip PCT	intraperitoneal	7
PCT-2	ABPC	v-Abl	Virus-accelerated ip PCT	intraperitoneal	12
PCT-3	J3PC	v-Raf + v-Myc	Virus-accelerated ip PCT	intraperitoneal	4
PCT-4	KiPC	IL-6 transgene	Transgene-accelerated ip PCT	intraperitoneal	3
PCT-5	IL6PC	IL-6 transgene	Spontaneous PCT	gut-associated lymphoid tissue	8
PCT-6	TEPC, LPC, MOPC	none	Pristane oil-induced ip PCT	intraperitoneal	18
BCL-1	IL6LN	IL-6 transgene	Spontaneous pre-malignant PCT	gut-associated lymphoid tissue	6
BCL-2	Pre B v-Abl (a.k.a. ABLS)	v-Abl	Virus-accelerated Pre-B lymphoma	bone marrow + spleen	6
BCL-3	BCL^Eμ	c-Myc in Igμ locus	Spontaneous BCL	lymph nodes	3
BCL-4	BCL^Cα	c-Myc in Igα locus	Spontaneous BCL	lymph nodes	3

ISSN: 1471-2164