Table 3 Top scoring reporter metabolites (p- values < 0.05)
From: Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus
Metabolisma | Metabolite | Number of neighbours | Z-score | p-value |
|---|---|---|---|---|
A, E, N | Carbamoyl phosphate | 5 | 4.341 | < 0.001 |
N | N-Carbamoyl-L-aspartate | 2 | 2.878 | 0.002 |
A, E, N | Carbamate | 2 | 2.772 | 0.003 |
Co, N | Uracil | 5 | 2.626 | 0.004 |
A | L-Citrulline | 3 | 2.484 | 0.006 |
A | 4-Imidazolone-5-propanoate | 2 | 2.480 | 0.007 |
Co, N | Uracil (extracellular) | 1 | 2.210 | 0.014 |
N | Orotidine-5-phosphate | 2 | 2.182 | 0.015 |
C | Melibiose (extracellular) | 1 | 2.092 | 0.018 |
C | Raffinose (extracellular) | 1 | 2.092 | 0.018 |
A | N-Formimino-L-glutamate | 2 | 2.087 | 0.018 |
L | Trihexadecanoylglycerol | 1 | 2.075 | 0.019 |
A | L-Arginine (extracellular) | 1 | 2.075 | 0.019 |
A | L-Ornithine (extracellular) | 1 | 2.075 | 0.019 |
L | Phosphatidylethanolamine | 2 | 2.047 | 0.020 |
L | Phosphatidylcholine | 2 | 2.047 | 0.020 |
L | Choline phosphate | 2 | 2.047 | 0.020 |
L | Ethanolamine phosphate | 2 | 2.047 | 0.020 |
A | 3-Methyl-2-oxopentanoate | 3 | 1.980 | 0.024 |
Co | Nicotinate | 2 | 1.979 | 0.024 |
C | Melibiose | 3 | 1.958 | 0.025 |
A, C, L | Glycerol (extracellular) | 1 | 1.949 | 0.026 |
N | (S)-Dihydroorotate | 2 | 1.937 | 0.026 |
C, L | 1,2-Dihexadecanoyl-sn-glycerol | 7 | 1.924 | 0.027 |
C | N-Acetylneuraminate | 1 | 1.907 | 0.028 |
C | Itaconate | 1 | 1.884 | 0.030 |
C | Itaconyl-CoA | 1 | 1.884 | 0.030 |
C | Raffinose | 2 | 1.870 | 0.031 |
A, C, N | D-Ribose | 2 | 1.860 | 0.031 |
A, C, L | Glycerol | 4 | 1.804 | 0.036 |
C, Co, N | Deoxyribose | 1 | 1.768 | 0.038 |
A | 2-Aminoacrylate | 1 | 1.746 | 0.040 |
A, N | GDP | 6 | 1.659 | 0.049 |
N | Orotate | 2 | 1.659 | 0.049 |
L | (R)-5-Diphosphomevalonate | 2 | 1.650 | 0.049 |