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Figure 1 | BMC Genomics

Figure 1

From: Characterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes

Figure 1

Local alignment of human and horse OAS1 promoters. BLAST2 alignment of the 1000 bp upstream of the transcription start for human OAS1 and equine OAS1 genes. The following BLAST parameters were used: a mismatch penalty of -1 and word size of 7. Lower case masking of repeats was used. The alignment shows that the sequence from ~800 bp to ~-350 bp in the horse promoter is similar to a region of the human promoter interrupted by a 200 bp Alu repeat (~-811 bp ~-590 bp). The horse microsatellite is shown in underlined bold and corresponds to a smaller dinucleotide repeat in the human sequence. Numbering shown in the alignments is from the translation ATG start sites.

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