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Table 2 Equine OAS1 single nucleotide polymorphisms and microsatellites

From: Characterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes

Region AccessionDQ536887 Alleles Residue Amino Acid Type Frequency Polymorphism
- 3640 C - - 0.25 Transition
   T    0.75  
- 3687 G - - 0.65 Transversion
   T    0.35  
- 3718 A - - 0.65 Transition
   G    0.35  
- 3724 C - - 0.65 Transition
   T    0.35  
- 3825 C - - 0.35 Transition
   T    0.65  
- 3830 A - - 0.85 Transversion
   T    0.15  
- 3973 C - - 0.65 Transition
   T    0.35  
- 4032–4063 - - - - GT repeat
- 4234 C - - 0.65 Transition
   T    0.35  
- 4333 C - - 0.35 Transition
   T    0.65  
- 4455 C - - 0.08 Transversion
   G    0.92  
- 4487 C - - 0.88 Transition
   T    0.12  
- 4501 C - - 0.65 Transition
   T    0.35  
- 4531 A - - 0.08 Transition
   G    0.92  
5' UTR 4598 C - - 0.65 Transversion
   G    0.35  
5' UTR 4625 A - - 0.35 Transversion
   C    0.65  
Exon 1 4690 A 18Tyr Uncharged Polar 0.85 Transition
   G 18Cys Uncharged Polar 0.15  
Exon 1 4783 C 49Ala Nonpolar 0.35 Transition
   T 49Val Nonpolar 0.65  
Intron 1 5609 C - - 0.67 Transition
   T    0.33  
Exon 2 5701 C 77Leu Nonpolar 0.64 Transition
   T 77Leu   0.36  
Exon 2 5743 C 91Phe Nonpolar 0.33 Transition
   T 91Phe   0.67  
Exon 2 5765 A 99Lys Basic Polar 0.65 Transition
   G 99Glu Acidic Polar 0.35  
Exon 2 5776 A 102Arg Basic Polar 0.38 Transition
   G 102Arg   0.62  
Exon 2 5786 A 106Lys Basic Polar 0.38 Transition
   G 106Glu Acidic Polar 0.62  
Exon 2 5920 G 150Pro Nonpolar 0.08 Transversion
   T 150Pro   0.92  
Exon 3 9374 C 209Arg Basic Polar 0.85 Transition
   T 209Cys Uncharged Polar 0.15  
Exon 4 12714 C 264Asn Uncharged Polar 0.59 Transversion
   G 264Lys Basic Polar 0.41  
Intron 4 12810 C - - 0.64 Transition
   T    0.36  
Intron 4 12853 A - - 0.55 Transition
   G    0.45  
Intron 5 13628 A - - 0.55 Transversion
   T    0.45  
Intron 5 13649 C - - 0.46 Transversion
   G    0.54  
Exon 6 15320 C 370Arg Basic Polar 0.75 Transition
   T 370Trp Nonpolar 0.25  
3' UTR 15410 G - - 0.62 Transversion
   T    0.38  
3' UTR 15537 G - - 0.19 Transversion
   T    0.81  
- 15798–15855 - - - - GT repeat
  1. SNPs and microsatellites identified from sequencing the OAS1 proximal promoter and exons from 13 equine individuals and CHORI BAC 100I10. Positions are identified from the genomic consensus sequence submitted to GenBank [GenBank: DQ536887].