Skip to main content
Figure 6 | BMC Genomics

Figure 6

From: The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

Figure 6

Alignment of Elfn proteins. Predicted amino acid sequences from Elfn1 (A930017N06Rik) and Elfn2 (Lrrc62) from the mouse were aligned with CLUSTALW. Amino acids are colour-coded by chemical properties: blue: acidic; green: hydroxyl/amine/basic/Q; magenta: basic; red: small, hydrophobic (including aliphatic Y). Brackets indicate the extent of predicted motifs, including signal sequence (SS), six LRRs (the notch under the bracket indicates the end of the conserved N-terminal portion of each LRR), LRR-CT domain, fibronectin type-3 (FN3) domain and a transmembrane domain (TM). No recognizable LRR-NT domain was predicted. Note that the final LRR comprises the highly conserved N-terminal half-repeat only (consensus: LxxLxxLxLxxN). Identical residues are indicated by an asterisk, highly conservative substitutions by two dots and conservative substitutions by a single dot.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us