This figure shows the second quartile of a protein sequence alignment of T. castaneum cys-loop LGIC subunits, for the full image please see Additional file 2. Drosophila Dα1 and RDL are included for comparison. Loops implicated in ligand binding (LpA-F) as well as transmembrane regions (TM) are indicated. The two cysteines forming the cys-loop are highlighted in black shading. Putative N-glycosylation sites are boxed and amino acid residues altered by RNA editing are circled.