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Table 6 Cox proportional hazards analysis of SEP-based classification

From: Integrated analysis of independent gene expression microarray datasets improves the predictability of breast cancer outcome

Training dataset

Tested on all 286 patients

Tested on 209 ER+ patients

 

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Rosetta

1.85 (1.26–2.74)

0.0019

1.97 (1.25–3.10)

0.0031

Combined

1.81 (1.23–2.66)

0.0028

2.42 (1.52–3.87)

0.0002

  1. The 60-gene profiles obtained from the training datasets were validated by all and ER-positive patients in Veridex dataset. Patients were grouped using the median SEP score as threshold.
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BMC Genomics

ISSN: 1471-2164

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