Figure 1

Structure of the bovine SILV mRNA including alternative transcripts. Position of exons (open boxes) and introns (solid line) in the SILV genomic sequence are indicated. Protein domains according to [4,31] are shown: SIG: signal peptide, NTD: N-terminal domain, PKD: polycystic kidney domain, RPT: repeat domain, KRG: Kringle-like domain, TM: transmembrane domain, CTD: C-terminal domain, G1, G2, G3: undefined domains. E: SILV exon.* Numbers in the SILV protein diagram represent the first amino acid of the respective domain. ** Numbers for the SILV transcripts represent the first nucleotide for the respective exon or the last constitutive nucleotide of an alternative transcript. fm: frame shift mutation. Length [in bp] of the alternative c SILV transcripts is indicated in red (left), the missing part relative to the constitutive SILV transcript (nucleotides and amino acids) is indicated in green (right).