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Figure 6 | BMC Genomics

Figure 6

From: Comparison of the contributions of the nuclear and cytoplasmic compartments to global gene expression in human cells

Figure 6

The lists of nucleus-enriched and cytoplasm-enriched transcripts were analyzed for potential interactions by the proteins represented by the transcripts. The analysis was performed with Osprey software, which employs The Biogrid [49], a database of protein-protein interactions based on in vitro, in vivo, yeast two-hybrid system, and affinity-capture mass spectrometry experimentation. The main grouping of interacting proteins that resulted is presented here. Those proteins that represented nucleus-enriched transcripts are marked with an 'N'. The proteins are labeled with the corresponding gene name, and the annotation information for the proteins is provided in Table 1. Each protein is color coded according to its annotation heading. The experimental system(s) employed to determine the protein-protein relationship is indicated by the color coding of the arrows.

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