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Table 1 T. whipplei isolates used in this study and percentage of conserved CDSs identified through CGH analysis

From: Comparative genomic analysis of Tropheryma whipplei strains reveals that diversity among clinical isolates is mainly related to the WiSP proteins

Isolate designation Sample origin Clinical manifestations Patient (sex, age) Geographical origin % conserved CDSs
Twist Aortic valve EW M42 Canada 100.00
Endo 5 Heparinized blood EW M61 France 99.63
Endo 7 Aortic valve EW M67 Portugal 99.75
Slow 1B Faeces CWD, digestive relapse F34 France 99.88
Slow 2 Duodenal biopsy CWD F70 France 99.50
ART 1 Synovial fluid CWD M68 France 99.13
Neuro 1 Cerebrospinal fluid CWD, neurologic relapse M57 Germany 99.88
Neuro 2 Cerebrospinal fluid CWD with neurologic involvement F40 France 99.63
Dig 7 Heparinized blood CWD M64 France 99.00
Dig 9 Heparinized blood CWD M35 France 99.38
Dig 10 Cerebrospinal fluid CWD with neurologic involvement M46 Germany 99.63
Dig ADP 11 Mesenteric lymph node CWD M56 France 99.50
Dig Neuro 14 Cerebrospinal fluid CWD with neurologic involvement M50 Germany 99.88
Dig 15 Cerebrospinal fluid CWD with neurologic involvement M60 Germany 97.76
Dig Musc 17 Muscle CWD F73 France 99.25
Dig Neuro 18 Cerebrospinal fluid CWD with neurologic involvement M68 France 99.25
  1. CWD = Classic Whipple's disease
  2. EW = Endocarditis due to T. whipplei
  3. M: male; F: female