Potential IGF-I regulated or co-regulated genes. The vertical axis corresponds to log-transformed fold-change. The 31 contrasts listed in Table 1 are ordered along the horizontal axis. The thick black line represents fold-changes associated with IGF-I across the 31 contrasts. Red lines represent five genes for which fold-changes across contrasts are most positively associated with those of IGF-I (Mup3, Es31, Igfals, Keg1, Socs2). Green lines represent five genes for which fold-changes across contrasts are most negatively associated with those of IGF-I (Scd2, Slc16a7, Pcp4l1, Snm1, Igfbp1). Additional files 1 and 2 provide plots for the top 40 genes most positively and negatively associated with the IGF-I expression pattern among all contrasts.