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Table 2 Overview of Differential Expression Results

From: Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging

Contrast Symbol

IGF1 [log2(FC)]

Upregulated

Downregulated

snell5

-3.96*

129

187

snell25

-3.91*

65

86

ames4A

-3.20*

347

273

ames10A

-3.05*

314

214

ames22A

-1.55*

229

171

ames3B

-3.79*

567

420

ames6B

-3.18*

501

470

ames12B

-2.92*

424

307

ames24B

-1.03*

305

193

little3

-2.46*

359

291

little6

-2.54*

328

314

little12

-2.23*

200

310

little24

-1.99*

206

269

GHR-KO

-4.68*

8

38

GHR-KI1

-0.40

5

5

GHR-KI2

-5.29*

24

13

B6

-0.28

1

7

Gender

0.05

243

284

cr(2, 6)

-0.08

93

67

cr(2, 6)df

-0.85*

22

24

cr(20, 22)

0.26

65

116

cr(5, 22)

0.49

279

529

met

0.24

127

172

met (db/db)

0.20

166

523

glip

0.03

80

49

gm

0.32

114

107

ros

0.11

51

65

soy

0.17

45

32

lowfat1

0.20

6

8

lowfat2

-0.31

96

54

age

0.20

494

458

  1. For each contrast, the number of probesets significantly upregulated and downregulated at a significance level of 0.05 is listed. The log-transformed fold-change [log2(FC)] associated with the insulin-like growth factor I (IGF1) transcript is also listed.
  2. *test for differential expression significant with P < 0.05