Table 2 Results of over-representation analysis of gene ontologies
Gene Ontology | GO ID | Number of probes on array | Number of genes on array | Number of genes in gene cluster | Raw p-value | FDR-corrected p-value |
|---|---|---|---|---|---|---|
Cluster I-Immune Function and Development | ||||||
MHC class I protein binding | GO:0042288 | 7 | 7 | 2 | 0.0000 | 0.0561 |
Neurite morphogenesis | GO:0048812 | 62 | 60 | 3 | 0.0032 | 0.1289 |
Cell fate determination | GO:0001709 | 59 | 45 | 2 | 0.0106 | 0.1807 |
Cluster II-Cell Growth | ||||||
Vesicle transport along actin filament | GO:0030050 | 181 | 9 | 2 | 0.0000 | 0.0251 |
SWR1 complex | GO:0000812 | 182 | 10 | 2 | 0.0000 | 0.0119 |
Cortical actin cytoskeleton | GO:0030864 | 183 | 11 | 2 | 0.0000 | 0.0122 |
Condensed nuclear chromosome | GO:0000794 | 13 | 13 | 2 | 0.0001 | 0.0168 |
Histone acetylation | GO:0016573 | 186 | 14 | 2 | 0.0001 | 0.0178 |
Actin filament | GO:0005884 | 187 | 15 | 2 | 0.0001 | 0.0190 |
Meiosis | GO:0007126 | 51 | 51 | 3 | 0.0002 | 0.0269 |
M phase of mitotic cell cycle | GO:0000087 | 97 | 96 | 3 | 0.0024 | 0.0779 |
Cluster III-Metabolism | ||||||
Sterol metabolism | GO:0016125 | 12 | 12 | 3 | 0.0000 | 0.0001 |
Trypsin activity | GO:0004295 | 14 | 14 | 3 | 0.0000 | 0.0001 |
Positive regulation of protein metab. | GO:0051247 | 18 | 18 | 3 | 0.0000 | 0.0002 |
Cholesterol metabolism | GO:0008203 | 18 | 18 | 3 | 0.0000 | 0.0002 |
Cluster IV-Stress | ||||||
Lytic vacuole | GO:0000323 | 42 | 42 | 3 | 0.0001 | 0.2378 |
Lysosome | GO:0005764 | 54 | 54 | 3 | 0.0004 | 0.3168 |
Response to UV | GO:0009411 | 6 | 5 | 1 | 0.0004 | 0.1620 |
Replicative cell aging | GO:0001302 | 5 | 5 | 1 | 0.0004 | 0.1296 |
Response to water deprivation | GO:0009414 | 5 | 5 | 1 | 0.0004 | 0.1080 |
Response to reactive oxygen species | GO:0000302 | 7 | 7 | 1 | 0.0008 | 0.1349 |