Figure 1
From: Fasting induces a biphasic adaptive metabolic response in murine small intestine
Design of the microarray study. A) Each of 3 microarrays per time point (0, 12, 24 and 72 hours of fasting) was hybridized with mRNA from a different pool of 2 animals, while mRNA obtained from a pool of 6 control intestines was used as reference. B) Numbers of significantly changed genes due to fasting: among 4304 genes differentially expressed (P < 0.01, ≥ 1.4-fold change), those changed at more than one time point of starvation are shown in the overlapping areas of the Venn diagram. C) Hierarchical clustering of microarrays shows segregation of different starvation time points into distinct branches of the dendrogram.