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Table 3 Top 10 known genes altered by VPA in MC3T3-E1 cells

From: Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors

Gene

Fold Change

Welch Test

Induced

  

   Glutathione S-transferase, theta 1

2.345

1.73E-06

   Glutaminyl-peptide cyclotransferase

2.334

2.36E-05

   Sorbitol dehydrogenase 1

2.328

1.91E-06

   Procollagen, type XI, alpha 1

2.216

7.84E-06

   Solute carrier family 9, isoform 3 regulator 1

2.203

2.33E-06

Suppressed

  

   Proteasome subunit, beta type 10

-2.035

3.33E-06

   Adaptor-related protein complex AP-4, sigma 1

-2.119

4.39E-07

   RIKEN cDNA 2310039E09 gene

-2.759

1.48E-05

   Tenascin N

-2.913

8.53E-06

   Chemokine (C-X-C motif) receptor 6

-3.728

1.56E-07

  1. All genes were present at a FDR of 0.01 (99% confidence) relative to the vehicle control, DMSO.