Table 5 Genes differentially regulated more than two-fold by all three HDIs
From: Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors
Gene Description | TSA | MS-275 | VPA |
|---|---|---|---|
Induced | Fold Change | ||
   A kinase anchor protein 12 (Akap12) | 9.5 | 2.0 | 2.6 |
   Glutaminyl-peptide cyclotransferase (Qpct)* | 5.0 | 2.4 | 2.3 |
   Glutathione S-transferase, alpha 4 (Gsta4) | 8.5 | 2.3 | 3.1 |
   Ral GEF with PH domain and SH3 binding motif 2 (Ralgps2) | 2.2 | 2.0 | 2.1 |
   Solute carrier family 9, isoform 3 regulator 1 (Slc9a3r1)* | 5.6 | 2.5 | 2.2 |
   Sorbitol dehydrogenase 1 (Sdh1)* | 4.5 | 2.4 | 2.3 |
Suppressed | Â | Â | Â |
   Adaptor-related protein complex AP-4, sigma 1 (Ap4s1) | -4.9 | -2.5 | -2.1 |
   Proteasome (prosome, macropain) subunit, beta type 10 (Psmb10)* | -5.4 | -2.1 | -2.0 |