From: Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors
 | MC3T3 Cells Microarray | Primary Osteoblasts qRT-PCR | |||
---|---|---|---|---|---|
Growth factor/receptor | TSA | MS-275 | VPA | TSA | VPA |
 | Fold Change | ||||
Amphiregulin | 7.10 | 2.74 | 1.82 | 24.8 | 2.56 |
Brain-derived neurotrophic factor | 2.51 | 1.66 | 1.77 | ND | ND |
Fibroblast growth factor 7 | -5.80 | -1.10 | -1.17 | -29.9 | 1.05 |
Frizzled 1 | -2.17 | -1.25 | -1.24 | -2.53 | -1.44 |
Frizzled 4 | 2.23 | 1.37 | 1.53 | 1.79 | 2.57 |
Interleukin 1 receptor-like 1 | -1.63 | -2.04 | -1.83 | -52.1 | 1.04 |
Interleukin 17 receptor c | -2.62 | -1.50 | -1.43 | ND | ND |
Smoothened | -2.60 | -1.53 | -1.17 | ND | ND |