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Table 3 Genes differentially expressed during ES cell differentiation in serum versus serum-free defined media (BMP4 2 ng/ml)

From: Dynamic transcription programs during ES cell differentiation towards mesoderm in serum versus serum-freeBMP4 culture

Set 1 – Chemokine ligands (Day 8) Symbol Synonyms Genbank ID BMP4 Serum
Hydroxyprostaglandin dehydrogenase 15 Hpgd   NM_008278.1 2.22 4.4
Src-like adaptor Sla Slap NM_009192 1.29 .90
Pleckstrin Plek   NM_019549.1 1.31 4.9
Triggering receptor expressed on myeloid cells-like 1 Treml1   XM_128641.3 1.67 12.6
Glycoprotein 5 (platelet) Gp5 GPV NM_008148.2 1.52 8.9
2810484G07Rik     2.07 13.5
Chemokine (C-X-C motif) ligand 7 Cxcl7 b-TG1; CTAP3; LDGF; MDGF;NAP-2 NM_023785.1 1.07 4.8
Angiotensin receptor 1 Agtr1 AT1;AT1a;AT2R1 NM_177322.2 1.58 5.8
Arachidonate 12-lipoxygenase Alox12 Alox12p;P-12LO NM_007440.2 1.29 9.2
Chemokine (C-C motif) ligand 4 Ccl4 Act-2; MIP-1B NM_013652 1.81 19.5
Chemokine (C-X-C motif) ligand 4 Cxcl4 Pf4;Scyb4 NM_019932.1 3.85 29.0
ATPase, Ca2+ transporting, ubiquitous Atp2a3 Serca3 NM_016745.2 1.30 6.1
Chemokine (C-C motif) ligand 3 Ccl3 Mip1a;Scya3 NM_011337.1 1.75 11.8
Set 2 – Globins (Day 6) Symbol Synonyms Genbank ID BMP4 Serum
β-major globin Hbb-b1   AK002258 2.15 21.7
ζ-globin Hba-x   NM_010405.2 4.30 128.3
ε-y globin Hbb-y E-y NM_008221.2 1.80 38.1
Nuclear factor erythroid-2 (p45) Nfe2 p45NFE2 NM_008685.2 1.32 10.4
α-globin Hba-a1 Hba1 NM_008218.1 3.21 89.7
Band-3/anion exchanger 1 Slc4a1 Ae1;CD233;Band 3 NM_011403.1 1.19 26.2
Rik2510042H12    AK011092 1.01 4.1
Aminolevulinic acid synthase 2 Alas2 Alas-2 NM_009653.1 1.14 13.2
β h1-globin Hbb-bh1 betaH1 NM_008219.2 3.65 61.2
Set 3 – Blood (Day 8) Symbol Synonyms Genbank ID BMP4 Serum
Alpha hemoglobin stabilising protein AHSP AHSP;EDRF NM_133245.1 1.7 3.4
Myeloperoxidase Mpo   NM_010824 1.1 3.6
  Slc38a5 SN2; JM24 NM_172479.1 1.3 2.5
Glycophorin A Gypa CD235a;GPA NM_010369.2 2.1 5.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 Cited4 Mrg2 NM_019563 1.3 2.5
Mitoferrin Mscp Slc25a37 NM_030054.2 1.5 2.4
Kruppel-like factor 1 Klf1 Eklf NM_010635 1.8 3.6
Set 4 – Various (Day 16) Symbol Synonyms Genbank ID BMP4 Serum
FXYD domain-containing ion transport regulator 2 Fxyd2 Atp1g1 NM_007503 1.38 6.7
Thioether S-methyltransferase Temt   NM_009349 0.97 6.0
Mus musculus FXYD domain-containing ion transport regulator 2, transcript variant a Fxyd2 Atp1g1 NM_052824.1 1.16 5.7
Fibrinogen, alpha Fga Fib NM_010196.1 2.06 11.8
Kininogen-1 Kng1   NM_023125.2 6.25 37.3
Serum amyloid A 3 Saa3 Saa-3 NM_011315 1.04 4.5
Deleted in azoospermia-like Dazl Dazla;Tpx-2;Tpx2 NM_010021.2 0.91 3.8
Fibrinogen, alpha Fga Fib NM_010196.1 2.57 14.3
Chitinase 3-like 1 Chi3l1 brp-39;Brp39;Gp39 NM_007695.1 1.75 7.3
Kininogen II    NM_201375.1 1.73 7.9
Set 5 – Macrophage (Day 16) Symbol Synonyms Genbank ID BMP4 Serum
Neutrophil cytosolic factor 2 Ncf2 Ncf-2; p67phox NM_010877 2.05 3.56
Complement component 1q beta C1qb   NM_009777.1 1.13 4.63
Matrix metalloproteinase 12 Mmp12 Mmel NM_008605.1 3.17 8.53
Complement component 3 C3 ASP;Plp NM_009778.1 2.17 10.46
CD68 antigen Cd68 gp110;Scard1 NM_009853 1.84 5.58
Macrophage expressed gene 1 Mpeg1   XM_129176 3.08 6.74
TYRO protein tyrosine kinase binding protein Tyrobp DAP12;KARAP;Ly83 NM_011662.2 2.80 4.81
Myosin IF Myo1f   NM_053214.1 1.64 3.33
Hematopoietic protein 1 Hemp1   NM_153505.2 1.41 4.22
Glutathione S-transferase, alpha 3 Gsta3 Gst2-3 NM_010356.2 1.73 8.67
Glycoprotein (transmembrane) nmb Gpnmb Dchil;ipd NM_053110 1.55 6.63
Pleckstrin homology, Sec7 and coiled/coil domains 4 Pscd4 2510004M07Rik NM_028195 1.54 3.83
B-cell leukaemia/lymphoma-2 related protein A1b Bcl2a1b A1-b NM_007534 2.49 6.35
Complement component 1q, gamma C1qg C1qc NM_007574.1 1.26 5.27
Fc receptor, IgG, low affinity III Fcgr3 CD16 NM_010188.2 2.10 5.84
Lysozyme Lyzs Lys;Lzm;;Lzp NM_017372.2 5.80 21.72
Chemokine (C-C motif) ligand 9 Ccl9 CCF18;MRP-2; NM_011338 2.26 3.85
B-cell leukemia 2 related protein A1d Bcl2a1d A1-d NM_007536 2.51 4.49
EGF-like module containing, mucin-like, hormone receptor-like 1 Emr1 F4/80; Ly71;TM7LN3 NM_010130.1 1.54 3.44
Set 6 – Day 16 Symobol Synonyms Genebank ID BMP4 Serum
Insulin-like growth factor 1 Igf1 C730016P09Rik;Igf-1;Igf-I NM_010512.2 1.6 4.8
  Prss35   NM_178738.1 4.7 5.9
Protein tyrosine phosphatase, non-receptor type substrate 1 Ptpns1 CD172a; SHP-1;SHPS-1; XM_149178.1 2.2 3.7
Apolipoprotein A-II Apoa2 Alp-2;Apoa-2;ApoA-II;Hdl-1 NM_013474.1 9.8 57.4
Spondin 2, extracellular matrix protein Spon2 ;M-spondin;Mindin NM_133903.2 2.0 12.0
Set 7 – Stem and late Day 16 Symbol Synonyms Genbank ID BMP4 Serum
Fbox 15 Fbxo15    0.96 4.4
Aurora kinase C Aurkc AIE1;AIK3;Stk13 NM_020572.1 0.94 4.1
2200001I15Rik    NM_183278.1 0.94 6.4
Hypothetical protein LOC236546   AF067061 NM_199060.1 0.85 3.8
Eukaryotic translation initiation factor 1A LOC195150   XM_111306.1 0.80 9.3
Similar to Pro-Pol-dUTPase polyprotein; RNaseH LOC386244   XM_359136.1 0.88 5.2
Similar to hypothetical protein FLJ35105 LOC245109   XM_142517.3 0.89 3.7
Down regulated in renal cell carcinoma Drr1 TU3A AK044219 0.57 9.3
Set 8 – Cardiac Day 16 Symbol Synonyms Genbank ID BMP4 Serum
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Atp2a1 SERCA1 NM_007504.2 6.9 1.1
Cholinergic receptor, nicotinic, gamma Chrng Achr-3;Acrg NM_009604.2 4.5 1.0
Myosin, light polypeptide 1    BC059087.1 8.0 1.1
Alpha actin, skeletal muscle Acta1 Acta-2;Acts;Actsk-1 NM_009606.1 25.3 1.2
Tropomyosin 2 beta Tpm2 Tpm-2;Trop-2 NM_009416.2 11.6 1.3
Cholinergic receptor, nicotinic, alpha Chrna1 Achr-1;Acra NM_007389.2 4.1 1.0
Troponin C2, fast Tnnc2 Tncs NM_009394.2 5.7 0.9
Neurofilament 3, medium Nef3 NF-M;NF160;Nfm NM_008691.1 4.5 1.1
Myosin heavy chain Myh8   XM_354617 6.7 1.1
Cholinergic receptor, nicotinic, alpha 1 Chrna1 Achr-1;Acra NM_007389.2 5.4 1.1
Set 9 – Cardiac 2 Day 6 Symbol Synonyms Genbank ID BMP4 Serum
a-Actin, cardiac Actc1 Actc-1 NM_009608.1 31.2 3.6
Somatostatin Sst Smst;SOM;SRIF;SS NM_009215.1 10.8 2.2
Myosin, light polypeptide 7, regulatory Myl7 MLC2a;MYL2A;;RLC-A NM_022879.1 14.3 4.7
Myosin, heavy polypeptide 7, cardiac muscle, beta Myh7 Myhc-b;Myhcb NM_080728.1 8.2 2.4
a-Actin, cardiac Actc1 Actc-1 NM_009608.1 26.3 3.5