Likelihood surface for the E. coli K12 chromosome. This representation of the likelihood surface of the E. coli K12 chromosome (NC_000913) is based on the MOBS model (see Methods). The two axes represent relative chromosome length so that every point represents the likelihood analysis on the pair of chromosome locations [S1, S2]. The grey scale inset shows the conversion of log likelihood to grey value, with the maximum log likelihood (LLmax) as black and the bars indicating -10 decrements. Since not every pair of chromosome locations was sampled the points are dispersed. The likelihood analysis is symmetrical around the diagonal so the two maxima are identical and represent just one pair of chromosome locations, but interchanging leading and lagging strands. The negative lines represent the location of the annotated ori and ter. The positive lines represent the maximum likelihood (ML) values and Monte Carlo estimated 95% ranges.