Skip to main content
Figure 4 | BMC Genomics

Figure 4

From: The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia

Figure 4

The Bok-protein is localized to CA3. Micrographs showing immunohistochemical detection of Bok (Bcl-2 related ovarian killer) protein expression in the hippocampus of C57/bl6 mice. A, Overview of the hippocampal formation (original magnification (OM) 10×). Bok preferentially localizes to th CA3 subfield, with some staining in the dentate gyrus. Apart from the hippocampus stining is visible in the cortex. B,C,D,E Staining in the CA3 subfield (B), in the CA3-CA2 transition (C), in the CA1 field (D), and in the CA1-subiculum transition (E) (OM 20×). In CA2 only few single neurons are detectable that stain positive for Bok, in CA1 staining is absent and is evident again in the subiculum. F, Close-up of CA3 neurons (OM 60×). Although quite specifically localized to CA3 Bok displays a patchy staining of neurons within this subfield.

Back to article page