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Table 2 List of the TGFβ1 interactome hubs.

From: Genes involved in TGFβ1-driven epithelial-mesenchymal transition of renal epithelial cells are topologically related in the human interactome map

GB accession ID EntrezGene ID Gene Symbol Gene description Log ratio
AK002171 7046 TGFBR1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53 kDa) 1,04
NM_001456 2316 FLNA filamin A, alpha (actin binding protein 280) 0,77
NM_002026 2335 FN1 fibronectin 1 0,73
NM_001100 58 ACTA1 actin, alpha 1, skeletal muscle 0,62
NM_005157 25 ABL1 v-abl Abelson murine leukemia viral oncogene homolog 1 0,61
AK024230 7532 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0,61
NM_000389 1026 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0,60
NM_002859 5829 PXN paxillin 0,58
NM_053056 595 CCND1 cyclin D1 0,55
NM_004087 1739 DLG1 discs, large homolog 1 (Drosophila) 0,54
NM_006597 3312 HSPA8 heat shock 70 kDa protein 8 0,49
NM_004346 836 CASP3 caspase 3, apoptosis-related cysteine peptidase 0,45
NM_003029 6464 SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0,45
NM_005658 7185 TRAF1 TNF receptor-associated factor 1 0,44
NM_032904 5781 PTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) 0,42
NM_005544 3667 IRS1 insulin receptor substrate 1 0,25
NM_003246 7057 THBS1 thrombospondin 1 0,20
NM_005243 2130 EWSR1 Ewing sarcoma breakpoint region 1 -0,46
NM_003177 6850 SYK spleen tyrosine kinase -0,48
NM_021105 5359 PLSCR1 phospholipid scramblase 1 -0,48
NM_001753 857 CAV1 caveolin 1, caveolae protein, 22 kDa -0,50
AF130085 1499 CTNNB1 catenin (cadherin-associated protein), beta 1, 88 kDa -0,56
NM_015400 4088 SMAD3 SMAD, mothers against DPP homolog 3 (Drosophila) -0,62
NM_001101 60 ACTB actin, beta -0,63
NM_007315 6772 STAT1 signal transducer and activator of transcription 1, 91 kDa -0,94
AK024192 11030 RBPMS RNA binding protein with multiple splicing -0,97
NM_000633 596 BCL2 B-cell CLL/lymphoma 2 -1,41
  1. Columns show: the GenBank accession number, the EntrezGene ID, the Gene symbol, the gene's description and the geometric mean of the log2 ratio given in Additional file 1, column N, indicating the level of gene expression.