Table 1 Summary of datasets analyzed in this study

Reference

Gilchrist et al. (2006) [8]

[11]

Nau et al. (2002) [9]

Jeffrey et al. (2006) [10]

Organism

Mouse

Mouse

Human

Human

Cells

BMM

RAW264.7

Mph

Mph

Stimulators

LPS, CpG, PAM2, PAM3, PIC, R848

LPS, CpG, PAM2, PAM3, PIC, R848

LPS, PIC

LPS

Time-points

0 h, 20 m, 40 m, 1 h, 80 m, 2 h, 8 h*, 24 h*

0 h, 1 h*, 2 h*, 4 h, 8 h*, 24 h*

0 h, 1 h, 2 h, 6 h, 12 h, 24 h

0 h, 4 h

Microarray

Affymetrix MG430 2.0

Two-channel oligonucleotide chip (Operon)

Affymetrix HU6800

Affymetrix HGU133A

# distinct annotated genes

15,277

11,442

5,215

7,981

Replicates

Triplicates

Quadrareplicates

One (two at time 0 h)

Duplicates