Persistence of coding and non-coding sequences in related species. A: Sequence identity % to human genome (B: Identity % to D. melanogaster genome) in whole genome alignments. CDS (green) > 80% protein coding regions; NC: 100% non-coding, non repetitive regions. Plain line: most conserved alignments, dotted line: 2nd fraction of conserved alignments. For each plot, the spacing is relative to the estimated geological divergence time (not to scale for A. gambiae)  (Species abbreviations are given in Additional file 1).