Table 1 Genes with significantly altered expression at transition phase only in the sigB-proficient C. glutamicum strain (RES167).
CDS | Gene name | Predicted function | m-value |
|---|---|---|---|
AMINO ACID METABOLISM AND PROTEOLYSIS | |||
cg0998 | trypsin-like serine protease | 1.57 | |
cg1129 | aroF | phospho-2-dehydro-3-deoxyheptanoate aldolase | 1.87 |
cg1783 | soxA' | glycine/D-amino acid oxidase – fragment | 1.16 |
cg1930 | secreted trypsine-like serine protease | 1.29 | |
cg2418 | ilvE | branched-chain amino acid aminotransferase | 1.48 |
cg2884 | dipeptide/tripeptide permease | 1.21 | |
cg1453 | leuB | 3-isopropylmalate dehydrogenase | -1.04 |
cg2588 | proB | glutamate 5-kinase protein | -1.43 |
CARBON METABOLISM AND TRANSPORT | |||
cg1479 | glgP1 | glycogen phosphorylase | 1.17 |
cg2796 | MmgE/PrpD family protein | 1.19 | |
cg0699 | guaB2 | inositol-monophosphate dehydrogenase, CBS domain | -1.07 |
cg0756 | cstA | putative carbon starvation protein A | -1.61 |
cg0812 | dtsR1 | acetyl/propionyl-CoA carboxylase beta chain | -1.24 |
cg1790 | pgk | phosphoglycerate kinase | -1.06 |
cg1791 | gap | glyceraldehyde-3-phosphate dehydrogenase | -2.01 |
cg2704 | sugar ABC-transporter, permease component | -1.38 | |
cg2705 | amyE | sugar ABC-transporter, binding protein | -1.42 |
cg3096 | aldehyde dehydrogenase | -1.17 | |
cg3219 | ldh | L-lactate dehydrogenase | -1.10 |
cg3380 | short-chain dehydrogenase | -1.06 | |
STRESS DEFENSE MECHANISMS | |||
cg1028 | restriction-modification system, methylase | 1.04 | |
cg0291 | intradiol ring-cleavage dioxygenase | 1.90 | |
cg1073 | glyoxylase | 1.06 | |
cg2078 | methionine-R-sulfoxide reductase | 1.09 | |
cg2999 | FAD-dependent oxidoreductase | 1.12 | |
cg3141 | hmp | flavohemoprotein involved in NO detoxification | 1.61 |
cg1595 | uspA2 | universal stress protein UspA | -1.11 |
cg3100 | dnaK | heat shock protein Hsp70 | -1.58 |
MEMBRANE PROCESSES | |||
cg0465 | conserved hypothetical membrane protein | 1.21 | |
cg0467 | cobalamin/Fe3+-siderophores transport system | 1.22 | |
cg1082 | putative membrane protein | 1.39 | |
cg1130 | uppS1 | undecaprenyl pyrophosphate synthetase | 1.50 |
cg1344 | narG | nitrate reductase 2, alpha subunit | 1.01 |
cg1345 | narK | nitrate/nitrite transporter | 1.36 |
cg1622 | ABC-type multidrug/protein/lipid transport system | 1.06 | |
cg1623 | divalent heavy-metal cations transporter | 1.18 | |
cg2215 | membrane protein | 1.25 | |
cg2377 | mraW | S-adenosylmethionine-dependent methyltransferase | 1.03 |
cg2425 | permease | 1.01 | |
cg2440 | permease | 1.23 | |
cg2676 | ABC-type peptide/nickel transport system | 1.18 | |
cg2810 | Na+/H+-dicarboxylate symporter family | 1.43 | |
cg3337 | putative membrane protein | 1.18 | |
cg3338 | putative membrane protein | 1.04 | |
cg1108 | porC | putative porin precursor | -1.25 |
cg1109 | porB | anion-specific porin precursor | -1.84 |
cg1349 | membrane protein, CBS domain | -1.79 | |
cg1639 | membrane protein, CBS domain | -1.23 | |
cg1640 | membrane protein, CBS domain | -1.52 | |
cg2467 | ABC-transporter ATP-binding protein | -1.33 | |
cg2468 | ABC-transporter permease component | -1.26 | |
cg2511 | putative membrane protein | -1.80 | |
cg3175 | membrane protein | -1.36 | |
cg3195 | flavin-containing monooxygenase involved in K+ transport | -1.16 | |
PHOSPHORUS METABOLISM AND REGULATION | |||
cg0866 | phosphoribosyl transferase | 1.02 | |
cg1718 | phospholipid-binding protein | 1.02 | |
cg2842 | phoU | phosphate uptake regulator | 1.31 |
cg2888 | phoR | phosphate starvation two component response regulator | 1.11 |
cg3194 | membrane-associated phosphoesterase | 1.06 | |
cg2513 | phoH2 | phosphate starvation-inducible protein | -1.22 |
REGULATORY PROCESSES | |||
cg1083 | cgtS10 | probable two component sensor kinase | 1.23 |
cg1084 | cgtR10 | two component response regulator | 1.47 |
cg2614 | bacterial regulatory proteins, TetR family | 1.18 | |
cg3230 | transcriptional regulator, λ repressor-like | 1.13 | |
TRANSCRIPTION AND TRANSLATION | |||
cg0572 | rplJ | 50S ribosomal protein L10 | -1.43 |
cg0573 | rplL | 50S ribosomal subunit protein L7/L12 | -1.37 |
cg2092 | sigA | RNA polymerase sigma 70 factor | -1.03 |
VITAMINS/COFACTORS BIOSYNTHESIS AND TRANSPORT | |||
cg0999 | molybdenum cofactor biosynthesis protein | 1.02 | |
cg1132 | coaA | pantothenate kinase | 1.11 |
cg0899 | glutamine amidotransferase/pyridoxine biosynthesis | -1.29 | |
FUNCTION UNKNOWN | |||
cg0096 | conserved hypothetical protein | 3.08 | |
cg0097 | conserved hypothetical protein | 2.57 | |
cg0753 | secreted protein | 1.04 | |
cg0806 | conserved hypothetical protein | 1.20 | |
cg0935 | conserved hypothetical protein | 1.28 | |
cg1091 | hypothetical protein | 1.85 | |
cg1131 | conserved hypothetical protein | 1.59 | |
cg1286 | conserved hypothetical protein | 1.55 | |
cg1304 | secreted protein | 1.58 | |
cg1417 | GCN5-related N-acetyltransferase | 1.41 | |
cg2057 | secreted protein | 1.35 | |
cg2105 | conserved hypothetical protein | 1.14 | |
cg2797 | conserved hypothetical protein | 1.21 | |
cg2850 | conserved hypothetical protein | 1.14 | |
cg3022 | conserved hypothetical protein | 1.15 | |
cg3329 | conserved hypothetical protein | 1.09 | |
cg3330 | putative secreted protein | 1.71 | |
cg0177 | hypothetical protein | -1.21 | |
cg0757 | conserved hypothetical protein | -1.20 | |
cg0838 | DEAD-box helicase | -1.05 | |
cg0892 | conserved hypothetical protein | -1.03 | |
cg1013 | hypothetical protein | -1.30 | |
cg1167 | putative secreted protein | -1.14 | |
cg1911 | putative secreted protein | -1.07 | |
cg2464 | conserved hypothetical protein | -1.32 | |